What are various methods of tubal patency test ?
There are 3 main type of tubal patency tests-
The advantage laparoscopy of is that any corrective surgery can be done during same procedure.
When we should consider tubal patency test ?
What are the chances of pregnancy after tubal patency test ?
Pregnancy chances depend upon various complex factors like
What is ERA ?
-ERA is an abbreviation for Endometrial ReceptivityArray or Analysis.
-This is specialised genetic test carried out on a tiny portion of the woman’s uterine lining to determine the most appropriate day to transfer embryo during an IVF cycle.
Who can benefit from ERA?
Endometrial Receptivity Array test is done in couple with repeated implantation failure.
How is ERA test done?
Is there any limitation of ERA test?
Ovarian reserve is the number as well as quality of the remaining eggs in both ovaries at a given age.
Egg quality directly affects embryo development & the ‘take home baby ‘rate.
Ovarian Reserve Test ( ORT ) helps to determine the chances of natural conception as well as with treatment.
It is very important to identify women with low ovarian reserve so that they can take important decisions regarding their own fertility in a timely manner.
Following are the risk factors for Decreased ovarian reserve :
Ovarian reserve should be tested in following conditions also :
Ovarian reserve can be determined with Ovarian Reserve Test ( ORT ):
Caution while interpreting result of ORT :
Ultrasound imaging makes use of ultrasound waves to visualise internal organ of body.
Baseline Pelvic USG
1st visit USG is done in detail to assess following conditions which may affect fertility :
Antral Follicle Count Scan (AFC scan)
Ovarian reserve is checked by doing Antral Follicle Count ( AFC) during initial visit itself.
Antral Follicles are tiny 2-10 mm follicle, each containing 1 egg.
Follicular Monitoring Scan
Growth of the follicle, uterus lining thickness & ovulation timing are checked by doing follicular monitoring USG.
Oocyte retrieval & Embryo transfer
Retrieval of oocytes ( eggs ) from ovaries & transfer of embryos into the uterus are done under ultrasound guidance.
USG guided ovarian cyst aspiration
Cyst aspiration can be done as day care procedure to drain ovarian cysts.
We offer following USG services using 2D & 3 D technique.
Use of ultrasound in men
For men ultrasound is done in few select cases to assess following conditions:
Who can benefit from Ovulation Induction :
What to expect during Ovulation Induction
Success rate after OI
Usually 8- 16% success after 1 cycle of OI is expected.
It depends on many factors like underlying pathology , age of woman , semen quality & duration of infertility , condition of fallopian tubes etc.
General outline of PRP treatment
PRP for ovarian rejuvenation
PRP for endometrial rejuvenation
ICSI is advanced modification of IVF to fertilise egg with sperm .
During ICSI each oocyte is held & injected individually with selected sperm by trained embryologist .
That is why the term ICSI- Intra Cytoplasmic ( of oocyte here ) Sperm Injection is used .
Basic outline of genetic testing of the embryo :
1st step -Genetic counselling to determine if the couple needs genetic test of the embryo & which type of test should be done .
2nd step -IVF /ICSI procedure to get embryos.
3rd step -Blastocyst culture to get embryos with best implantation potential .
4th step -Embryo biopsy : Collection of 5-7 cells from blastocyst stage embryo using special microsurgical instruments .
- Implantation & future growth potential of the embryo is not compromised when biopsy is done on blastocyst stage embryos.
5th step - The genetic material , DNA is extracted from these cells & tested for genetic diseases using specially made genetic test probes.
6th step - Transfer of normal embryo in womb
-In most cases cryopreservation of embryo is required till the final result of genetic test is available .
There are 3 type of embryo genetic testing :
(1) Preimplantation Genetic Testing for Aneuploidies ( PGT-A):
Who can benefit from PGT-A ?
(2) Pre Implantation Genetic Testing for Monogenic Diseases (PGT-M):
Who can benefit from PGT-M ?
(3)Pre Implantation Genetic tests for Structural Rearrangement ( PGT- SR )
Who can benefit from PGT-SR ?
3rd party reproduction & gestational surrogacy
-Third party reproduction involves use of donor sperm, donor egg or donor embryo to conceive or taking help of gestational surrogate to carry the pregnancy.
-The couple who will raise the baby after delivery are called ‘Intended Parents’.
-The person who will donate the sperm, egg , embryo or carry the pregnancy is the ‘Third Party ‘.
-Third party reproduction involves teamwork of your fertility physician, psychological counsellor, gamete donor agencies, gestational surrogacy agency, social worker & lawyer .
Who may need egg donation ?
Who may need sperm donation ?
Who may need gestational surrogacy ?
It’s very important to avoid any conflict in 3rd party reproduction :
Ask for transparency in all steps of the treatment.
The aim of this discussion is to make anyone with curious mind to understand these condition better. It is not equivalent to detailed in person individualised consultation.
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