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Recurrent IVF Failure Treatment in Indore

In several steps of reproduction, implantation is among the most crucial ones. A synchronised dialogue among the embryonic and maternal tissues, a receptive endometrium, and a competent blastocyst is required for a successful implantation. Invasion, adhesion, and apposition are involved in the implantation process.

Implantation is often referred to as intrauterine gestational sac’s ultrasonographic evidence. Recurrent IVF Failure or Recurrent Implantation Failure is frustrating for people undergoing the treatment because of the failed implantation of normal embryos in the uterus and failed foetus development. When multiple IVF cycles fail to implant, the patient is considered to experience Recurrent IVF Failure or Recurrent Implantation Failure (RIF).

It is common to come across couples who have undergone IVF treatment or ICSI treatment or test tube baby treatment more than once and have not succeeded. There can be many causes for such unfortunate condition.

Cost of Recurrent IVF Failure Treatment in Indore

  • ERA or Endometrial Receptive Array- 35,000 INR to 40,000 INR
    Sperm testing – 500 INR to 1000 INR
  • Diagnostic hysteroscopy- 10,000 INR to 50,000 INR
  • PGT-A- 10,000 INR to 80,000 INR
  • Sperm DNA fragmentation test- 7,000 INT to 25,000 INR
  • Immunologic Tests- 20,000 INR to 30,000 INR

Causes Of Recurrent IVF Failure Or Recurrent Implantation Failure

Oocytes or egg numbers diminish, and genetic abnormality of oocytes’ higher proportion occurs when women get older. Incidences of biochemical pregnancy or failed implantation increase with maternal age, specifically in those at 30 or above. Several known aspects contribute to Recurrent IVF Failure or Recurrent Implantation Failure. Few common causes are:

  • Chromosomally abnormal embryos,
  • Uterus which is not ready to accept embryo (abnormal uterine receptivity), and other uterine abnormalities, such as polyps, fibroid tumours, and congenital defects
  • Wrong embryo selection
  • Poor oocyte or sperm quality
  • Problems during embryo transfer process
  • High levels of mental stress in the women
  • Paternal and maternal age
  • Genetic embryo(s) competency
  • Inflamed fallopian tubes
  • Chronic infections
  • Autoimmune factors
  • Endometrium
  • Obesity
  • Hormone abnormalities
  • Maternal drug, alcohol, tobacco, or other environmental toxins usage

Testing For Recurrent IVF Failure Or Recurrent Implantation Failure

Evaluation is crucial for patients who experience recurrent IVF failure or recurrent implantation failure.

  • Immunologic Tests
  • Preimplantation Genetic Testing for Aneuploidy (PGT-A)
  • Endometrial Receptivity Assay (ERA)
  • Sperm DNA fragmentation test
  • Detailed uterine assessment, such as Uterine Evaluation/Hysterosalpingogram (HSG)
  • Appropriate evaluation of immunologic, hormonal, and genetic factors
  • Reproductive and medical history of the couple

Maternal Tests For Recurrent IVF Failure or Recurrent Implantation Failure:

  • Karyotype
  • Intracytoplasmic morphological sperm injection (IMSI)
  • Sperm DNA

Paternal Tests For Recurrent IVF Failure or Recurrent Implantation Failure:

  • Anatomical screening
  • Hormonal screening
  • Immunology screening
  • Thrombophilia (clotting) screen

Treatment For Recurrent IVF Failure Or Recurrent Implantation Failure

Several treatment options to assist in reducing the failed implantation incidence include the following:

  • Blood thinning medications, hormonal supplements, antibiotic therapy
  • Several pelvic corrective procedures, including the uterine treatment process
  • Limited immunotherapy
  • PGT-A with IVF
  • Endometrial receptivity array (ERA)
  • Using embryo selection techniques 
  • Endometrial scratch

Yaami Infertility And IVF Center

A good fertility clinic should have expert fertility specialists or fertility consultants who can focus on all the above issues and try to find the reason for the failed IVF treatment. In many cases, a correctable cause might be found which can pave the way for a successful IVF cycle. It becomes imperative for the couple to consult an infertility specialist who has the experience of treating many such cases of IVF treatment failures since such experiences helps the fertility specialist make a tailor made plan for the couple and take them to a successful outcome.

Yaami Infertility and IVF Center provides state-of-the-art care and attention to every patient depending on sound ethical and medical parameters. Patients dealing with recurrent IVF or implantation failure must empower themselves by seeking emotional support and expert care from our specialists when they plan to build their families.

What is Recurrent IVF Failure or Recurrent Implantation Failure?

Recurrent IVF Failure or Recurrent Implantation Failure occurs when implantation is lacking after several embryo transfers.

How to test Recurrent IVF Failure or Recurrent Implantation Failure?

Recurrent IVF Failure or Recurrent Implantation Failure can be tested through Endometrial Receptive Array or ERA tests.

How to identify Recurrent IVF Failure or Recurrent Implantation Failure?

You can identify Recurrent IVF Failure or Recurrent Implantation Failure if you notice breast tenderness, nausea, headache, bleeding, cramping, lower back pain, or mood swings.

Why does Recurrent IVF Failure or Recurrent Implantation Failure occur?

Among the most common causes of Recurrent IVF Failure or Recurrent Implantation Failure is impaired endometrial receptivity.

Is Recurrent IVF Failure or Recurrent Implantation Failure treatable?

Many treatment options are accessible to treat Recurrent IVF Failure or Recurrent Implantation Failure, including preimplantation genetic testing for aneuploidies (PGT-A), improving sperm quality and endometrium receptivity, anticoagulant, immunotherapy, lifestyle intervention, etc.

Hope this was helpful for basic understanding.

The aim of this discussion is to make anyone with curious mind to understand these condition better. It is not equivalent to detailed in person individualised consultation.

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