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DNA Fragmentation Index

The DNA of the sperms can get damaged in various conditions like men who smoke, men with varicocele, couples with repeated miscarriages or repeated IVF failures and in many people without any known problems. If the DNA gets damaged, the chance of natural pregnancy and the pregnancy through IUI treatment or IVF treatment goes down. So in such cases, the infertility doctor or the infertility specialist needs to correct the cause of high DNA damage to Sperms, give medication to improve DNA damage and in certain cases, use the sperms directly from the testis as these Sperm are known to have lesser DNA damage. These corrections in DNA damage are important for couples who are undergoing IUI treatment, IVF treatment or IVF cycle (also known as test tube baby treatment) as well as ICSI treatment.

Hope this was helpful for basic understanding.

The aim of this discussion is to make anyone with curious mind to understand these condition better. It is not equivalent to detailed in person individualised consultation.

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