Who can benefit from Ovulation Induction :
What to expect during Ovulation Induction
Success rate after OI
Usually 8- 16% success after 1 cycle of OI is expected.
It depends on many factors like underlying pathology , age of woman , semen quality & duration of infertility , condition of fallopian tubes etc.
General outline of PRP treatment
PRP for ovarian rejuvenation
PRP for endometrial rejuvenation
ICSI is advanced modification of IVF to fertilise egg with sperm .
During ICSI each oocyte is held & injected individually with selected sperm by trained embryologist .
That is why the term ICSI- Intra Cytoplasmic ( of oocyte here ) Sperm Injection is used .
Basic outline of genetic testing of the embryo :
1st step -Genetic counselling to determine if the couple needs genetic test of the embryo & which type of test should be done .
2nd step -IVF /ICSI procedure to get embryos.
3rd step -Blastocyst culture to get embryos with best implantation potential .
4th step -Embryo biopsy : Collection of 5-7 cells from blastocyst stage embryo using special microsurgical instruments .
- Implantation & future growth potential of the embryo is not compromised when biopsy is done on blastocyst stage embryos.
5th step - The genetic material , DNA is extracted from these cells & tested for genetic diseases using specially made genetic test probes.
6th step - Transfer of normal embryo in womb
-In most cases cryopreservation of embryo is required till the final result of genetic test is available .
There are 3 type of embryo genetic testing :
(1) Preimplantation Genetic Testing for Aneuploidies ( PGT-A):
Who can benefit from PGT-A ?
(2) Pre Implantation Genetic Testing for Monogenic Diseases (PGT-M):
Who can benefit from PGT-M ?
(3)Pre Implantation Genetic tests for Structural Rearrangement ( PGT- SR )
Who can benefit from PGT-SR ?
3rd party reproduction & gestational surrogacy
-Third party reproduction involves use of donor sperm, donor egg or donor embryo to conceive or taking help of gestational surrogate to carry the pregnancy.
-The couple who will raise the baby after delivery are called ‘Intended Parents’.
-The person who will donate the sperm, egg , embryo or carry the pregnancy is the ‘Third Party ‘.
-Third party reproduction involves teamwork of your fertility physician, psychological counsellor, gamete donor agencies, gestational surrogacy agency, social worker & lawyer .
Who may need egg donation ?
Who may need sperm donation ?
Who may need gestational surrogacy ?
It’s very important to avoid any conflict in 3rd party reproduction :
Ask for transparency in all steps of the treatment.