Endometrial Receptive Array

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ERA

Endometrial Receptive Array

What is ERA ?
  • ERA is an abbreviation for Endometrial Receptivity Array or Analysis.
  • This is specialised genetic test carried out on a tiny portion of the woman’s uterine lining to determine the most appropriate day to transfer embryo during an IVF cycle.
Who can benefit from ERA ?
  • Endometrial Receptivity Array test is done in couple with repeated implantation failure.
How is ERA test done ?
  • Endometrial biopsy for ERA test can be done in natural ovulation cycle or after giving hormonal treatment.
  • After endometrial biopsy the genetic material is extracted from the endometrial tissue.
  • The extracted genetic material (RNA ) is tested for 236 genes which are normally expressed during implantation window.
  • The result of ERA is reported as pre receptive or non-receptive
  • ERA test may be repeated in some cases when report is pre or post receptive.
  • This guides us to decide the most suitable day for embryo transfer.
Is there any limitation of ERA test ?
  • A normal ERA test ( receptive ) does not guarantee delivery of a healthy baby.
  • Pregnancy may fail to start & continue if there is embryo abnormality.
  • ERA checks the receptivity of endometrium during physiological implantation window.
  • Similarly ERA cannot tell us about condition of uterus to carry pregnancy till healthy delivery.
Hope this was helpful for basic understanding .The aim of this discussion is to make anyone with curious mind to understand these condition better .It is not equivalent to detailed in person individualised consultation .Please contact us if you want to understand your treatment options.